LDG Series Ribbon Single-Cone Vacuum Dryer, GMP Compliant for Pharmaceutical API Drying

The LDG series ribbon type single cone vacuum mixer dryer is specifically configured for pharmaceutical API, pharmaceutical intermediates and heat-sensitive crystalline powder drying under GMP hygienic conditions. Featuring 316L stainless steel contact parts, CIP online cleaning and SIP online sterilization capabilities.

This vertical, fully enclosed batch vacuum drying equipment integrates drying, mixing and material dispersion functions. The vessel features a single cone structure with an internal hollow heating ribbon agitator. Both the external heating jacket and hollow ribbon can be fed with heat transfer medium simultaneously, achieving dual-path heating.

Operating under high vacuum and low temperature conditions, the ribbon drives material in up-and-down circulation turnover motion, ensuring uniform heating. The fixed vessel design eliminates rotary vacuum joints for better vacuum stability, while bottom hemisphere valve discharge ensures thorough material removal with no residue.

• Hygienic customizable: Mirror polishing, supports CIP online cleaning and SIP online sterilization, meeting pharmaceutical GMP regulations.
• Dual heating structure: Vessel jacket + hollow ribbon supply heat simultaneously, significantly increasing effective heating area and drying efficiency.
• Active ribbon agitation: Continuous material turnover disperses lumps; prevents filter cake and viscous materials from sticking to walls.
• Fixed vessel without rotation: No rotary vacuum joint, excellent overall sealing, stable operation under high vacuum conditions.
• Bottom large-diameter hemisphere valve discharge: Cone hopper structure enables almost complete material discharge with no dead corners.
• Fully enclosed batch operation: Suitable for heat-sensitive, easily oxidized and toxic materials; solvent recoverable.
• Simple operation: Automated batch control; available as single machine or complete system with vacuum unit and condensation recovery.

Wet material is fed into the cone vessel through the top feed port. The jacket and hollow ribbon are fed with hot water/thermal oil/low pressure steam while the vessel maintains high vacuum to lower solvent vaporization temperature.

The variable frequency driven ribbon agitator rotates, lifting material upward from the cone bottom along the vessel wall. Material falls back to the bottom by gravity, forming continuous circulation turnover that constantly renews the heating surface and accelerates solvent volatilization.

Volatilized solvent vapor passes through the top dust filter and is extracted by the vacuum unit, with optional external condenser for solvent recovery. After drying completion, the bottom hemisphere discharge valve opens for direct discharge.

Core advantages: Jacket + hollow ribbon dual heating, active agitation material turnover, low temperature vacuum drying, closed batch operation, residue-free discharge.

• Pharmaceutical API industry: Pharmaceutical intermediates, crystalline API and filter cake vacuum drying, meeting GMP clean production.
• Food and biological industry: Food additives, plant extracts and crystalline powder low-temperature drying.
• Fine chemical industry: Catalysts, dye intermediates, various filter cakes and easily oxidized powder drying, with solvent recovery.
• New energy and new materials: Lithium battery precursor, inorganic powder and crystalline material drying.
• Pesticide industry: Pesticide intermediates and filter cake crystalline material closed drying.

Contact us for detailed specifications and a factory quote.